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DALES (RAFT 3)
DALES (RAFT 3)
Drug Allergy Labels in the Elective Surgical Population
Drug Allergy Labels in the Elective Surgical Population
RAFT - Research and Audit Federation of Anaesthetists in Training
RAFT - Research and Audit Federation of Anaesthetists in Training
DALES was a cross-sectional, observational and descriptive three-day study commencing mid-2018, comprising three components, and was the 3rd RAFT national collaborative project.
DALES was designed to evaluate the prevalence of patient-reported and documented drug allergies relevant to anaesthesia in those undergoing elective procedures, and to better understand anaesthetists’ knowledge and attitudes towards allergy.
The study was composed of a:
Patient questionnaire: including allergies
Targeted patient follow-up: for those reporting beta-lactam or opioid allergies
Anaesthetist survey: including attitudes to drug allergy labels
Summary of results
Summary of results
Data was collected from 21,219 elective surgical patients across 213 hospitals.
6214/21,219 patients (29.3%) reported at least one drug allergy.
The most frequently implicated drug groups were antibiotics, NSAIDs and opioids.
Of the 8755 reported reactions, only 2462 (28.1%) were categorised as high risk of representing a genuine allergy after risk stratification.
A history suggestive of chronic spontaneous urticaria was associated with increased reporting of drug allergy.
Only 1473/4756 anaesthetists (31.0%) routinely discussed peri-operative allergy risk with patients.
Most anaesthetists would prescribe opioids when the reported reaction was consistent with side-effects, but 2269/4697 (48.3%) would still avoid the specific opioid listed.
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